Kary Mullis in the
1980s developed a revolutionary technique that is now the basis of
the global polymerase chain reaction (PCR) market. The basic concept
of PCR is to use a DNA polymerase to synthesize completely new
strands of DNA. These strands will be similar to the template DNA
strand used. One of the core requirements in the process is the
addition of a primer. This is required because a DNA polymerase can
only add a nucleotide to a 3’-OH group that already exists. The
primer helps the polymerase to add the first nucleotide. Using this
method, a scientist can create billions of copies of any specific
sequence he/she wants. The core components of PCR are therefore a DNA
template, a DNA polymerase, and nucleotides.
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The techniques used
in the global PCR market have created a giant scope of innovation in
the world of science in terms of DNA-based research molecular
diagnostics. PCR allows for the absolute quantification of DNA and
RNA, both of which are genetic materials.
Commercial Labs
Boost the Global PCR Market
Till recent times,
the global PCR market has found scope mostly in pharma and
biotechnology industries apart from research institutions. The rise
of commercial diagnostic laboratories is set to change this confined
trend. A large number of labs, both private commercial and
government, are beginning to prefer PCR for the accurate diagnosis of
life-threatening diseases including cancer and Ebola. Large players
in the diagnostics industry are now building standalone labs with
minimal infrastructure to provide PCR.
Player Trends and
Innovations that Drive the Global PCR Market
All the top
companies that operate in the global PCR market are currently working
on developments that enhance the functionalities in it. This includes
creating a broader list of tests and a higher level of specificity
and sensitivity. Some of the key innovations that have defined the
global PCR market today are the significant reduction in turnaround
time, the ability to create automated workflow, and higher
productivity. All developments in the global PCR market focus on the
fact that there needs to be an extremely high level of accuracy in
the detection and amplification of genetic materials.
There is a major
shift in technologies happening in the global PCR market. This
involves the increasing preference of real time and/or digital PCR
systems. The market’s innovations will create a stronger foundation
for future activities. For example, the introduction of QX200 Droplet
Digital PCR system by Bio-Rad offers a plethora of tests for
molecular diagnostics. Their improved workflow will reduce overall
costs in the global PCR market.
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Reagents and
Consumables Dominate the Global PCR Market
The largest products
segment in the 2013 global PCR market was reagents and consumables,
when it generated a total of US$4,072.2 million for multiple
companies. As for the applications segment, more than 48% of the 2013
global PCR market was held by life sciences. Clinical diagnostics
held more than 33% of the market share in the same category. Life
sciences dominates this category due to a greater level of acceptance
of PCR oriented methods in cancer research, which happens to be one
of the oldest application segments in the global PCR market.
Academics and research has remained the largest end user of the
global PCR market for the longest time and continued its dominance
till 2013.
The global
polymerase chain reaction market had a past worth of US$6.1 billion
at the end of 2013. Market analysts now say that this market is
currently developing at a compound annual growth rate of 6.6% between
2014 and 2020. If this growth rate remains unchanged, the global
polymerase chain reaction market could potentially be worth US$9.6
billion by 2020. With its wide application base and growing number of
commercial labs, the market is set to show a good deal of promise to
all the players in it.
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