Molecular
Cytogenetics Market
was valued at USD 469.2 million in 2013 and is estimated to reach a
market worth USD 1.97 billion in 2019 at a CAGR of 23.4% from 2013 to
2019.
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Molecular
cytogenetics is emerging as an indispensable tool in the field of
research and diagnosis. Until the advent of molecular cytogenetics
techniques in 1980s, chromosomal analysis was mainly based on banding
patterns. Although, the traditional banding techniques encountered
problems such as low resolution and poor quality analysis. However,
breakthrough in fluorescence in situ hybridization (FISH) and
array-comparative genomic hybridization (aCGH) techniques has
enhanced the diagnosis of chromosomal anomalies particularly in tumor
and hematological malignancies. Nowadays, cytogenetics techniques are
being considered mandatory in diagnosis and prognosis of leukemia.
The techniques are considered as a standard laboratory test since
they provide global screening of abnormalities. The scope of
molecular cytogenetics is increasing with the rising cancer
incidences worldwide and growing popularity of personalized
medicines.
The
ability of FISH technique to study cells at an interphase stage of
the cell cycle has made the technique a breakthrough in molecular
cytogenetics field. FISH technique is used in the research of diverse
applications such as cancer, cardiovascular and genetic disorder. The
impetus of FISH technique is a direct result of improved
understanding of sequence, structure and function of human genome.
Similarly, supported by technological advancements in fluorescent
microscopes and digital imaging, FISH technique has emerged as a
preferred tool in molecular cytogenetics. The technique facilitates
the analysis of sub-chromosomal regions and the identifications of
small translocations thereby, routinely used in clinical
applications. Owing to the techniques' sensitivity and specificity,
FISH is significantly used in number of cytogenetic and pathological
laboratories.
The
advent of aCGH is ushering new standards for the analysis of genome.
The technology has turned out to be a greatest driver for the
molecular cytogenetics market as it is overcoming the resolution
problems associated with traditional banding techniques. aCGH is
poised to witness a significant growth in the market and is likely to
emerge as the fastest growing technology segment. aCGH has propelled
the cytogenetics market from the microscopes to computers and thus,
facilitated simultaneous analysis of thousands of discrete regions of
the genome. Similarly, the technique is gaining popularity as one
assay performed on this technique is comparable to thousands of FISH
experiments and hence, saves time and cost. Moreover, the technique
is expected to rapidly supplant FISH technique owing to further
technological advancements in the technique. Likewise, increasing
sensitivity of the aCGH technique is preferred as a primary diagnosis
tool followed by validation with FISH. The technique is emerging as a
powerful tool for high resolution analysis of sub-microscopic
chromosomal abnormalities. aCGH is also evolving as a method of
choice for molecular cytogenetics by the researchers owing to its
work flow advantages and cost effectiveness.
North
America accounts for the largest share of the molecular cytogenetics
market followed by the European region. The markets for these regions
are driven by factors such as increased level of public awareness,
rising cancer incidences and large number of research institutes
engaged in cytogenetics field. However, Asia-Pacific region is likely
to emerge as the fastest growing region over the analysis period.
Cancer diagnosis is likely to witness a significant growth and emerge
as the fastest growing segment during analysis period with a CAGR of
more than 20%.
The
growing demand for molecular cytogenetics techniques in research and
data interpretation has resulted in quick expansion of manufacturers'
product portfolio. The manufacturers are focused on building
aggressive strategies for the development of innovative products that
would cater research and diagnostic sectors. The vendors are eager to
tap the emerging regions and end-users of this market. Major players
engaged in development of innovative molecular cytogenetics
techniques are Abbott laboratories, Affymetrix, Inc., Applies
Spectral Imaging, BI Biological Industries, Life Technologies
Corporation, Roche Diagnostics, Oxford Gene Technology, Illumina,
Inc., among others.
The
molecular cytogenetics market is segmented as follows:
Molecular
Cytogenetics Market, by Technology
FISH
aCGH
Molecular
Cytogenetics Market, by Application
Genetic
Disorders
Cancer
Personalized
Medicine
Others
Molecular
Cytogenetics Market, by Geography
North
America
Europe
Asia-Pacific
RoW
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