Non-Invasive
Prenatal Testing Market
was valued at USD 0.22 billion in 2013 and is expected to grow at a
CAGR of 37.6% from 2013 to 2019, to reach an estimated value of USD
3.62 billion in 2019.
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The
market for non-invasive prenatal testing is evolving rapidly due the
advantages it offers over the conventional prenatal screening and
diagnostic methods such as maternal serum screening, nuchal
translucency (NT) scan, amniocentesis and chorionic villus sampling
(CVS). These advantages include safety, accuracy, and no risk of
miscarriage. An NIPT is a non-invasive genetic screening test for the
common chromosomal abnormalities (trisomy 21, trisomy 18, trisomy 13,
monosomy X, etc.) observed in the fetuses of high risk pregnant women
(above the age of 35 years). Owing to its ability to detect the
presence of chromosomal abnormalities in fetuses of pregnant women as
early as 9 to 10 weeks of gestation, the market for non-invasive
prenatal testing is witnessing a rapid increase in demand from all
parts of the world.
MaterniT21
PLUS, verifi, Harmony, Panorama, NIFTY, PrenaTest and BambniTest are
the commercially available NIPTs in the market which are based on the
direct analysis of cell-free fetal DNA in the maternal blood. In
2012, MaterniT21 (a proprietary product of Sequenom, Inc.) accounted
for the largest share (36.6%) of the global NIPT market in terms of
revenue, owing to the fact that it was the first mover in the market
place. During the forecast period 2013 to 2019, it is likely to lose
some of its share due to increasing market penetration by other
aforementioned NIPTs such as Panorama and verifi.
High
incidence rate of babies born with certain type of chromosomal
abnormalities, growing trend of child bearing at advanced maternal
age and enhanced popularity of NIPT among gynecologists and high risk
pregnant women are some of the major factors anticipated to drive
growth of the NIPT market during the forecast period. Some of the
most commonly detected chromosomal aneuploidies include Down
syndrome, Edwards syndrome, Patau syndrome and monosomy X. On the
other hand, ethical and regulatory hurdles are expected to pose
significant challenges before the NIPT market to grow. Various
professional committees across the world believe that the
implementation of NIPT and the subsequent rise in uptake of prenatal
testing is likely to increase the incidence of abortions. Therefore,
professional groups such as The American College of Obstetricians and
Gynecologists (ACOG), International Society for Prenatal Diagnosis
and The Japan Society of Obstetrics and Gynecology have set up
guidelines that limit the use of non-invasive prenatal testing only
to pregnant women at high risk of chromosomal aneuploidies.
Geographically,
North America was the largest regional market in 2012 with a market
share of 64.5% of the total revenue generated globally, followed by
Europe. Almost every company operating in this market is adopting the
same business model of marketing their tests via alliances with
hospitals, diagnostic laboratories and physician offices. The
increasing penetration by test developers in European, Asia-Pacific
and Middle-East countries indicates promising growth in the near
future in these markets. Sequenom, Inc., Verinata Health, Inc. (now a
part of Illumina, Inc.), Ariosa Diagnostics, Natera, Inc., BGI
Health, LifeCodexx and Berry Genomics are the companies engaged in
providing non-invasive prenatal tests worldwide.
The
global non-invasive prenatal testing market is segmented as follows:
Non-Invasive
Prenatal Testing Market, by Test
MaterniT21
PLUS
verifi
Harmony
Panorama
NIFTY
PrenaTest
BambniTest
Non-Invasive
Prenatal Testing Market, by Geography
North
America
Europe
Asia-Pacific
Rest
of the World (RoW)
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